Micro/Nanoscience & Biotechnology 530/580.496

 

Prof. Tza-Huei (Jeff) Wang
class taught:   Mon and Wed, 2:00-3:20pm, Maryland 310
office:    108 Latrobe / 118 Clark

office number:   

410-516-7086
email:    thwang@jhu.edu

 

Syllabus  

Prerequisites:

Senior undergraduate students and graduate students in engineering and physical science

Textbook:

There is no textbook. The lecturing is mainly based on the notes, selected research articles of journals, and sections from the following references. The lecture notes and supplementary materials will be posted on the webpage.

References:

1. “Nanoelectromechanics in Engineering and Biology”, M. P. Hughes, (CRC Press)
2. “Microsystem Technology in Chemistry and Life Sciences”, A Manz & H. Becker, (Springer)
3. “Mechanics of Motor Proteins and the Cytoskeleton”, J. Howard, (Sinauer)
4. “Nano- and Micro-Electromechanical Systems - Fundamentals of Nano- and Microengineering”, S. E. Lyshevski (CRC Press)
5. “Fundamentals and Applications of Microfluidics”, N. T. Nguyen & S. T. Wereley
Grading: Homework 25 %,  Midterm exam 30 %, Lab (10 %), Presentation) 5 %, Final exam 30 %
Homework: Homework will be due one week after it has been given, except when otherwise advised. Homework must be submitted at the beginning of the class on the day it is due. Late submissions will be penalized 10 % for every day it is late up to one week. After one week, homework will not be accepted.
Midterm: Oct. 25, 2006
Final Presentations: Dec 11, 2006, see instruction
Final Exam: Will be posted on Dec 18. Deadline of submission is noon, Dec 21.

      Homework 1 (Due Sep. 27)      Solution for HW-1

      Homework 2 (Due Oct. 11)      Solution for HW-2

      Homework 3 (Due Nov. 22)     Solution for HW-3

      Final Exam Problems

Topics: Lecture notes Reading Material
1.      Introduction Introduction Feynman, Overview
2.      Scaling laws  Scaling Law
3.  Mechanical forces at the molecular scale Molecular Mechanical Forces-I

Molecular Mechanical Forces-II

Mechanical Forces
4.     Thermal forces and diffusion Thermal Forces Thermal Forces
5.      Microfluidics Microflow Micro flow
6.     Microfabrication Microfabrication 1   Microfabrication 2 Microfabrication-I, Microfabrication-II
7.      Microflow control (pumps & valves) Microflow Control Microflow Control
8.      Electrokinetics Electrokinetics Electrokinetics
9. Transverse diffusion in microfluidic system
10.  Nanobiosensor & Single-molecule analysis